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Metformin Attenuates Inflammatory Responses and Enhances Antibody Production in an Acute Pneumonia Model of Streptococcus pneumoniae

Metformin may potentially reverse various age-related conditions; however, it is unclear whether metformin can also mitigate or delay the deterioration of immunological resilience that occurs in the context of infections that are commonly observed in older persons. We examined whether metformin prom...

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Detalles Bibliográficos
Autores principales: Lee, Grace C., Moreira, Alvaro G., Hinojosa, Cecilia, Benavides, Raymond, Winter, Caitlyn, Anderson, Audrey C., Chen, Chang-Jui, Borsa, Noemi, Hastings, Gabrielyd, Black, Cody A., Bandy, Sarah M., Shaffer, Alexander, Restrepo, Marcos I., Ahuja, Sunil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261336/
https://www.ncbi.nlm.nih.gov/pubmed/35821804
http://dx.doi.org/10.3389/fragi.2022.736835