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Metformin Attenuates Inflammatory Responses and Enhances Antibody Production in an Acute Pneumonia Model of Streptococcus pneumoniae
Metformin may potentially reverse various age-related conditions; however, it is unclear whether metformin can also mitigate or delay the deterioration of immunological resilience that occurs in the context of infections that are commonly observed in older persons. We examined whether metformin prom...
Autores principales: | Lee, Grace C., Moreira, Alvaro G., Hinojosa, Cecilia, Benavides, Raymond, Winter, Caitlyn, Anderson, Audrey C., Chen, Chang-Jui, Borsa, Noemi, Hastings, Gabrielyd, Black, Cody A., Bandy, Sarah M., Shaffer, Alexander, Restrepo, Marcos I., Ahuja, Sunil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261336/ https://www.ncbi.nlm.nih.gov/pubmed/35821804 http://dx.doi.org/10.3389/fragi.2022.736835 |
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