Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice

Objective: Although PU.1/Spi1 is known as a master regulator for macrophage development and function, we have reported previously that it is also expressed in adipocytes and is transcriptionally induced in obesity. Here, we investigated the role of adipocyte PU.1 in the development of the age-associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ke Yun, De Angulo, Alejandra, Guo, Xin, More, Aditya, Ochsner, Scott A., Lopez, Eduardo, Saul, David, Pang, Weijun, Sun, Yuxiang, McKenna, Neil J., Tong, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261351/
https://www.ncbi.nlm.nih.gov/pubmed/35822007
http://dx.doi.org/10.3389/fragi.2021.803482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261351/
https://www.ncbi.nlm.nih.gov/pubmed/35822007
http://dx.doi.org/10.3389/fragi.2021.803482

Ejemplares similares