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Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice
Objective: Although PU.1/Spi1 is known as a master regulator for macrophage development and function, we have reported previously that it is also expressed in adipocytes and is transcriptionally induced in obesity. Here, we investigated the role of adipocyte PU.1 in the development of the age-associ...
Autores principales: | Chen, Ke Yun, De Angulo, Alejandra, Guo, Xin, More, Aditya, Ochsner, Scott A., Lopez, Eduardo, Saul, David, Pang, Weijun, Sun, Yuxiang, McKenna, Neil J., Tong, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261351/ https://www.ncbi.nlm.nih.gov/pubmed/35822007 http://dx.doi.org/10.3389/fragi.2021.803482 |
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