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The Dynamics of Somatic Mutagenesis During Life in Humans

From conception to death, human cells accumulate somatic mutations in their genomes. These mutations can contribute to the development of cancer and non-malignant diseases and have also been associated with aging. Rapid technological developments in sequencing approaches in the last few years and th...

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Detalles Bibliográficos
Autores principales: Manders, Freek, van Boxtel, Ruben, Middelkamp, Sjors
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261377/
https://www.ncbi.nlm.nih.gov/pubmed/35822044
http://dx.doi.org/10.3389/fragi.2021.802407