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Aging Leads to Increased Monocytes and Macrophages With Altered CSF-1 Receptor Expression and Earlier Tumor-Associated Macrophage Expansion in Murine Mesothelioma

Increased cancer incidence occurs with the emergence of immunosenescence, highlighting the indispensability of the immune system in preventing cancer and its dysregulation with aging. Tumor-associated macrophages (TAMs) are often present in high numbers and are associated with poor clinical outcomes...

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Detalles Bibliográficos
Autores principales: Duong, Lelinh, Pixley, Fiona J., Nelson, Delia J., Jackaman, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261395/
https://www.ncbi.nlm.nih.gov/pubmed/35821822
http://dx.doi.org/10.3389/fragi.2022.848925