Cargando…

Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA

Alzheimer’s disease (AD) is an age-associated neurodegenerative disorder characterized by progressive impairment of memory, thinking, behavior, and dementia. Based on ample evidence showing neurotoxicity of amyloid-β (Aβ) aggregates in AD, proteolytically derived from amyloid precursor protein (APP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Kaoru, Takayama, Ken-ichi, Hashimoto, Makoto, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261399/
https://www.ncbi.nlm.nih.gov/pubmed/35822056
http://dx.doi.org/10.3389/fragi.2021.721579