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Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA
Alzheimer’s disease (AD) is an age-associated neurodegenerative disorder characterized by progressive impairment of memory, thinking, behavior, and dementia. Based on ample evidence showing neurotoxicity of amyloid-β (Aβ) aggregates in AD, proteolytically derived from amyloid precursor protein (APP)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261399/ https://www.ncbi.nlm.nih.gov/pubmed/35822056 http://dx.doi.org/10.3389/fragi.2021.721579 |