Age and CMV-Infection Jointly Affect the EBV-Specific CD8(+) T-Cell Repertoire

CD8(+) T cells play an important role in protection against viral infections. With age, changes in the T-cell pool occur, leading to diminished responses against both new and recurring infections in older adults. This is thought to be due to a decrease in both T-cell numbers and T-cell receptor (TCR...

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Detalles Bibliográficos
Autores principales: Lanfermeijer, Josien, de Greef, Peter C., Hendriks, Marion, Vos, Martijn, van Beek, Josine, Borghans, José A. M., van Baarle, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261403/
https://www.ncbi.nlm.nih.gov/pubmed/35822032
http://dx.doi.org/10.3389/fragi.2021.665637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261403/
https://www.ncbi.nlm.nih.gov/pubmed/35822032
http://dx.doi.org/10.3389/fragi.2021.665637

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