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Age and CMV-Infection Jointly Affect the EBV-Specific CD8(+) T-Cell Repertoire

CD8(+) T cells play an important role in protection against viral infections. With age, changes in the T-cell pool occur, leading to diminished responses against both new and recurring infections in older adults. This is thought to be due to a decrease in both T-cell numbers and T-cell receptor (TCR...

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Detalles Bibliográficos
Autores principales:	Lanfermeijer, Josien, de Greef, Peter C., Hendriks, Marion, Vos, Martijn, van Beek, Josine, Borghans, José A. M., van Baarle, Debbie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261403/ https://www.ncbi.nlm.nih.gov/pubmed/35822032 http://dx.doi.org/10.3389/fragi.2021.665637

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