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Age-Associated Changes to Lymph Node Fibroblastic Reticular Cells

The decreased proportion of antigen-inexperienced, naïve T cells is a hallmark of aging in both humans and mice, and contributes to reduced immune responses, particularly against novel and re-emerging pathogens. Naïve T cells depend on survival signals received during their circulation among the lym...

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Detalles Bibliográficos
Autores principales: Kwok, Tina, Medovich, Shannon C., Silva-Junior, Ildefonso A., Brown, Elise M., Haug, Joel C., Barrios, Marliece R., Morris, Karina A., Lancaster, Jessica N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261404/
https://www.ncbi.nlm.nih.gov/pubmed/35821826
http://dx.doi.org/10.3389/fragi.2022.838943