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Identification of Somatic Mutations From Bulk and Single-Cell Sequencing Data

Somatic mutations are DNA variants that occur after the fertilization of zygotes and accumulate during the developmental and aging processes in the human lifespan. Somatic mutations have long been known to cause cancer, and more recently have been implicated in a variety of non-cancer diseases. The...

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Detalles Bibliográficos
Autores principales: Huang, August Yue, Lee, Eunjung Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261417/
https://www.ncbi.nlm.nih.gov/pubmed/35822012
http://dx.doi.org/10.3389/fragi.2021.800380