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Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

Introduction: Each year, a disproportionate number of the total seasonal influenza-related hospitalizations (90%) and deaths (70%) occur among adults who are >65 years old. Inflammasome activation has been shown to be important for protection against influenza infection in animal models but has n...

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Detalles Bibliográficos
Autores principales: Crooke, Stephen N., Goergen, Krista M., Ovsyannikova, Inna G., Kennedy, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261430/
https://www.ncbi.nlm.nih.gov/pubmed/35822051
http://dx.doi.org/10.3389/fragi.2021.719103