Geranylgeranylacetone Ameliorates Beta-Amyloid Toxicity and Extends Lifespan via the Heat Shock Response in Caenorhabditis elegans

Activation of a cytoprotective cellular pathway known as the heat shock response (HSR) is a promising strategy for the treatment of Alzheimer’s disease and other neurodegenerative diseases. Geranylgeranylacetone (GGA) is a commonly used anti-ulcer drug in Japan that has been shown to activate the HS...

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Detalles Bibliográficos
Autores principales: Mossiah, Isiah, Perez, Sabrina M., Stanley, Taylor R., Foley, Michaela K., Kim Guisbert, Karen S., Guisbert, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261441/
https://www.ncbi.nlm.nih.gov/pubmed/35821801
http://dx.doi.org/10.3389/fragi.2022.846977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261441/
https://www.ncbi.nlm.nih.gov/pubmed/35821801
http://dx.doi.org/10.3389/fragi.2022.846977

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