Non-HLA Gene Polymorphisms in the Pathogenesis of Type 1 Diabetes: Phase and Endotype Specific Effects

The non-HLA loci conferring susceptibility to type 1 diabetes determine approximately half of the genetic disease risk, and several of them have been shown to affect immune-cell or pancreatic β-cell functions. A number of these loci have shown associations with the appearance of autoantibodies or wi...

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Detalles Bibliográficos
Autores principales: Laine, Antti-Pekka, Valta, Milla, Toppari, Jorma, Knip, Mikael, Veijola, Riitta, Ilonen, Jorma, Lempainen, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261460/
https://www.ncbi.nlm.nih.gov/pubmed/35812428
http://dx.doi.org/10.3389/fimmu.2022.909020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261460/
https://www.ncbi.nlm.nih.gov/pubmed/35812428
http://dx.doi.org/10.3389/fimmu.2022.909020

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