FTD-associated mutations in Tau result in a combination of dominant and recessive phenotypes

Although mutations in the microtubules-associated protein Tau have long been connected with several neurodegenerative diseases, the underlying molecular mechanisms causing these tauopathies are still not fully understood. Studies in various models suggested that dominant gain-of-function effects und...

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Detalles Bibliográficos
Autores principales: Law, Alexander D., Cassar, Marlène, Long, Dani M., Chow, Eileen S., Giebultowicz, Jadwiga M., Venkataramanan, Anjana, Strauss, Roland, Kretzschmar, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261467/
https://www.ncbi.nlm.nih.gov/pubmed/35588988
http://dx.doi.org/10.1016/j.nbd.2022.105770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261467/
https://www.ncbi.nlm.nih.gov/pubmed/35588988
http://dx.doi.org/10.1016/j.nbd.2022.105770

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