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In vivo Mouse Intervertebral Disc Degeneration Models and Their Utility as Translational Models of Clinical Discogenic Back Pain: A Comparative Review

Low back pain is a leading cause of disability worldwide and studies have demonstrated intervertebral disc (IVD) degeneration as a major risk factor. While many in vitro models have been developed and used to study IVD pathophysiology and therapeutic strategies, the etiology of IVD degeneration is a...

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Detalles Bibliográficos
Autores principales: Tang, Shirley N., Walter, Benjamin A., Heimann, Mary K., Gantt, Connor C., Khan, Safdar N., Kokiko-Cochran, Olga N., Askwith, Candice C., Purmessur, Devina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261914/
https://www.ncbi.nlm.nih.gov/pubmed/35812017
http://dx.doi.org/10.3389/fpain.2022.894651