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Synthesis and Biological Evaluation of 5-Fluoro-2-Oxindole Derivatives as Potential α-Glucosidase Inhibitors

α-Glucosidase inhibitors are known to prevent the digestion of carbohydrates and reduce the impact of carbohydrates on blood glucose. To develop novel α-glucosidase inhibitors, a series of 5-fluoro-2-oxindole derivatives (3a ∼ 3v) were synthesized, and their α-glucosidase inhibitory activities were...

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Detalles Bibliográficos
Autores principales: Lin, Jing, Liang, Qi-Ming, Ye, Yuan-Na, Xiao, Di, Lu, Li, Li, Meng-Yue, Li, Jian-Ping, Zhang, Yu-Fei, Xiong, Zhuang, Feng, Na, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261963/
https://www.ncbi.nlm.nih.gov/pubmed/35815213
http://dx.doi.org/10.3389/fchem.2022.928295