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Disease-associated astrocytes in Alzheimer’s disease and aging

The role of non-neuronal cells in Alzheimer’s disease (AD) progression has not been fully elucidated. Using single-nucleus RNA-seq, we identified a population of disease associated astrocytes (DAAs) in an AD mouse model. The DAA population appeared at early disease stages and increased in abundance...

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Detalles Bibliográficos
Autores principales: Habib, Naomi, McCabe, Cristin, Medina, Sedi, Varshavsky, Miriam, Kitsberg, Daniel, Dvir-Szternfeld, Raz, Green, Gilad, Dionne, Danielle, Nguyen, Lan, Marshall, Jamie L., Chen, Fei, Zhang, Feng, Kaplan, Tommy, Regev, Aviv, Schwartz, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262034/
https://www.ncbi.nlm.nih.gov/pubmed/32341542
http://dx.doi.org/10.1038/s41593-020-0624-8