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Disease-associated astrocytes in Alzheimer’s disease and aging
The role of non-neuronal cells in Alzheimer’s disease (AD) progression has not been fully elucidated. Using single-nucleus RNA-seq, we identified a population of disease associated astrocytes (DAAs) in an AD mouse model. The DAA population appeared at early disease stages and increased in abundance...
Autores principales: | Habib, Naomi, McCabe, Cristin, Medina, Sedi, Varshavsky, Miriam, Kitsberg, Daniel, Dvir-Szternfeld, Raz, Green, Gilad, Dionne, Danielle, Nguyen, Lan, Marshall, Jamie L., Chen, Fei, Zhang, Feng, Kaplan, Tommy, Regev, Aviv, Schwartz, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262034/ https://www.ncbi.nlm.nih.gov/pubmed/32341542 http://dx.doi.org/10.1038/s41593-020-0624-8 |
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