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Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1

Diabetic kidney disease is a major cause of chronic kidney condition and the most common complication of diabetes. The cellular senescence participates in the process of diabetic kidney disease, but the specific mechanism is not yet clear. Cell cycle-related protein E2F transcription factor 1 (E2F1)...

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Detalles Bibliográficos
Autores principales: Liang, Dan, Li, Zhiyang, Feng, Zhaowei, Yuan, Zhiping, Dai, Yunli, Wu, Xin, Zhang, Fan, Wang, Yuanyuan, Zhou, Yuxia, Liu, Lingling, Shi, Mingjun, Xiao, Ying, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262145/
https://www.ncbi.nlm.nih.gov/pubmed/35814218
http://dx.doi.org/10.3389/fphar.2022.926211