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Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1
Diabetic kidney disease is a major cause of chronic kidney condition and the most common complication of diabetes. The cellular senescence participates in the process of diabetic kidney disease, but the specific mechanism is not yet clear. Cell cycle-related protein E2F transcription factor 1 (E2F1)...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262145/ https://www.ncbi.nlm.nih.gov/pubmed/35814218 http://dx.doi.org/10.3389/fphar.2022.926211 |