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Impaired in vitro Interferon-γ production in patients with visceral leishmaniasis is improved by inhibition of PD1/PDL-1 ligation

Visceral leishmaniasis (VL) is a neglected tropical disease that causes substantial morbidity and mortality and is a growing health problem in Ethiopia, where this study took place. Most individuals infected with Leishmania donovani parasites will stay asymptomatic, but some develop VL that, if left...

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Detalles Bibliográficos
Autores principales: Takele, Yegnasew, Adem, Emebet, Franssen, Susanne Ursula, Womersley, Rebecca, Kaforou, Myrsini, Levin, Michael, Müller, Ingrid, Cotton, James Anthony, Kropf, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262188/
https://www.ncbi.nlm.nih.gov/pubmed/35749568
http://dx.doi.org/10.1371/journal.pntd.0010544