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Impaired in vitro Interferon-γ production in patients with visceral leishmaniasis is improved by inhibition of PD1/PDL-1 ligation
Visceral leishmaniasis (VL) is a neglected tropical disease that causes substantial morbidity and mortality and is a growing health problem in Ethiopia, where this study took place. Most individuals infected with Leishmania donovani parasites will stay asymptomatic, but some develop VL that, if left...
Autores principales: | Takele, Yegnasew, Adem, Emebet, Franssen, Susanne Ursula, Womersley, Rebecca, Kaforou, Myrsini, Levin, Michael, Müller, Ingrid, Cotton, James Anthony, Kropf, Pascale |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262188/ https://www.ncbi.nlm.nih.gov/pubmed/35749568 http://dx.doi.org/10.1371/journal.pntd.0010544 |
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