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The bioengineered HALOA complex induces anoikis in chronic myeloid leukemia cells by targeting the BCR-ABL/Notch/Ikaros/Redox/Inflammation axis

Blast crisis (BC) is an outcome that arises during the treatment process of chronic myeloid leukemia (CML), which is possibly attained by the dysregulation of the Notch and Ikaros signaling pathways, BCR-ABL translocation, redox, and inflammatory factors. This study demonstrated that biotherapeutic...

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Detalles Bibliográficos
Autores principales: Singh, Vivek, Singh, Ranjana, Mahdi, Abbas Ali, Tripathi, Anil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262277/
https://www.ncbi.nlm.nih.gov/pubmed/35815090
http://dx.doi.org/10.25122/jml-2021-0230