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HIF and COX-2 expression in triple negative breast cancer cells with hypoxia and 5-fluorouracil

Our purpose was to understand the effects of normoxia or hypoxia on 5-fluorouracil (5-FU) treatment in triple negative breast cancer (TNBC) cells, and characterize the molecular changes in hypoxia inducible factors (HIFs) and cyclooxygenase-2 (COX-2) following treatment. Cell viability and protein l...

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Detalles Bibliográficos
Autores principales: Mori, Noriko, Mironchik, Yelena, Wildes, Flonné, Wu, Sherry Y., Mori, Kanami, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262285/
https://www.ncbi.nlm.nih.gov/pubmed/35814639