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PD-1 is expressed in cytotoxic granules of NK cells and rapidly mobilized to the cell membrane following recognition of tumor cells

The contribution of the T cell-related inhibitory checkpoint PD-1 to the regulation of NK cell activity is still not clear with contradictory results concerning its expression and role in the modulation of NK cell cytotoxicity. We provide novel key findings on the mechanism involved in the regulatio...

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Detalles Bibliográficos
Autores principales: Pesini, Cecilia, Hidalgo, Sandra, Arias, Maykel A., Santiago, Llipsy, Calvo, Carlota, Ocariz-Díez, Maitane, Isla, Dolores, Lanuza, Pilar M., Agustín, M José, Galvez, Eva M, Ramírez-Labrada, Ariel, Pardo, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262365/
https://www.ncbi.nlm.nih.gov/pubmed/35813574
http://dx.doi.org/10.1080/2162402X.2022.2096359