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Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA
DNA-encoded library (DEL) technology is a powerful tool for small molecule identification in drug discovery, yet the reported DEL selection strategies were applied primarily on protein targets in either purified form or in cellular context. To expand the application of this technology, we employed D...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262588/ https://www.ncbi.nlm.nih.gov/pubmed/35288754 http://dx.doi.org/10.1093/nar/gkac173 |