Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA

DNA-encoded library (DEL) technology is a powerful tool for small molecule identification in drug discovery, yet the reported DEL selection strategies were applied primarily on protein targets in either purified form or in cellular context. To expand the application of this technology, we employed D...

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Detalles Bibliográficos
Autores principales: Chen, Qiuxia, Li, You, Lin, Chunrong, Chen, Liu, Luo, Hao, Xia, Shuai, Liu, Chuan, Cheng, Xuemin, Liu, Chengzhong, Li, Jin, Dou, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262588/
https://www.ncbi.nlm.nih.gov/pubmed/35288754
http://dx.doi.org/10.1093/nar/gkac173

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