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Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication

Antiviral innate immunity represents the first defense against invading viruses and is key to control viral infections, including SARS-CoV-2. Body temperature is an omnipresent variable but was neglected when addressing host defense mechanisms and susceptibility to SARS-CoV-2 infection. Here, we sho...

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Detalles Bibliográficos
Autores principales: Los, Bruna, Preußner, Marco, Eschke, Kathrin, Vidal, Ricardo Martin, Abdelgawad, Azza, Olofsson, Didrik, Keiper, Sandra, Paulo-Pedro, Margarida, Grindel, Alica, Meinke, Stefan, Trimpert, Jakob, Heyd, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262603/
https://www.ncbi.nlm.nih.gov/pubmed/35713540
http://dx.doi.org/10.1093/nar/gkac513