TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway

The E3 ubiquitin ligase TRIM25 is a key factor in the innate immune response to RNA viruses. TRIM25 has been shown to play a role in the retinoic-acid-inducible gene-1 (RIG-I) pathway, which triggers expression of type 1 interferons upon viral infection. We and others have shown that TRIM25 is an RN...

Descripción completa

Detalles Bibliográficos
Autores principales: Choudhury, Nila Roy, Trus, Ivan, Heikel, Gregory, Wolczyk, Magdalena, Szymanski, Jacek, Bolembach, Agnieszka, Dos Santos Pinto, Rute Maria, Smith, Nikki, Trubitsyna, Maryia, Gaunt, Eleanor, Digard, Paul, Michlewski, Gracjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262604/
https://www.ncbi.nlm.nih.gov/pubmed/35736141
http://dx.doi.org/10.1093/nar/gkac512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262604/
https://www.ncbi.nlm.nih.gov/pubmed/35736141
http://dx.doi.org/10.1093/nar/gkac512

Ejemplares similares