Cargando…

Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair

In nucleotide excision repair (NER), the xeroderma pigmentosum D helicase (XPD) scans DNA searching for bulky lesions, stalls when encountering such damage to verify its presence, and allows repair to proceed. Structural studies have shown XPD bound to its single-stranded DNA substrate, but molecula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Iwen, Mu, Hong, Geacintov, Nicholas E, Broyde, Suse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262607/ https://www.ncbi.nlm.nih.gov/pubmed/35713557 http://dx.doi.org/10.1093/nar/gkac496

Ejemplares similares

Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies
por: Mu, Hong, et al.
Publicado: (2012)

Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion–base stacking interactions
por: Reeves, Dara A., et al.
Publicado: (2011)

Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system
por: Kropachev, Konstantin, et al.
Publicado: (2014)

Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair
por: Ding, Shuang, et al.
Publicado: (2012)

Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex
por: Chakraborty, Sagnik, et al.
Publicado: (2018)

Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion
por: Donny-Clark, Kerry, et al.
Publicado: (2009)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Repair of gaps opposite lesions by homologous recombination in mammalian cells
por: Adar, Sheera, et al.
Publicado: (2009)

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence
por: Allgayer, Julia, et al.
Publicado: (2013)

Unusual sequence effects on nucleotide excision repair of arylamine lesions: DNA bending/distortion as a primary recognition factor
por: Jain, Vipin, et al.
Publicado: (2013)

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
por: Zhao, Junhua, et al.
Publicado: (2009)

Nucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clock
por: Bee, Leonardo, et al.
Publicado: (2015)

DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair
por: Chitale, Shalaka, et al.
Publicado: (2017)

Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
por: Kang, Tae-Hong, et al.
Publicado: (2011)

Chronic low-dose ultraviolet-induced mutagenesis in nucleotide excision repair-deficient cells
por: Haruta, Nami, et al.
Publicado: (2012)

AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair
por: Jarrett, Stuart G., et al.
Publicado: (2016)

Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage
por: Slyskova, Jana, et al.
Publicado: (2018)

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation
por: Liebelt, Frauke, et al.
Publicado: (2020)

Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins
por: Lindsey-Boltz, Laura A, et al.
Publicado: (2023)

A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N(4)-ethenocytosine
por: Chaim, Isaac A., et al.
Publicado: (2017)

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis
por: Cazzalini, Ornella, et al.
Publicado: (2014)

Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1
por: Arczewska, Katarzyna D., et al.
Publicado: (2013)

XPD-dependent activation of apoptosis in response to triplex-induced DNA damage
por: Kaushik Tiwari, Meetu, et al.
Publicado: (2013)

A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair
por: Ranes, Michael, et al.
Publicado: (2016)

Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A
por: Tsaalbi-Shtylik, Anastasia, et al.
Publicado: (2014)

XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage
por: Liu, Jing, et al.
Publicado: (2015)

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts
por: Sidorenko, Victoria S., et al.
Publicado: (2012)

Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β
por: Asagoshi, Kenjiro, et al.
Publicado: (2012)

Localization of xeroderma pigmentosum group A protein and replication protein A on damaged DNA in nucleotide excision repair
por: Krasikova, Yuliya S., et al.
Publicado: (2010)

Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair
por: Nishi, Ryotaro, et al.
Publicado: (2013)

The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair
por: Barnett, Jamie T, et al.
Publicado: (2020)

TREX1 degrades the 3′ end of the small DNA oligonucleotide products of nucleotide excision repair in human cells
por: Kim, Seon Hee, et al.
Publicado: (2022)

Requirement of transcription-coupled nucleotide excision repair for the removal of a specific type of oxidatively induced DNA damage
por: Sarmini, Leen, et al.
Publicado: (2023)

p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair
por: Wang, Qi-En, et al.
Publicado: (2013)

Genetic instability associated with loop or stem–loop structures within transcription units can be independent of nucleotide excision repair
por: Burns, John A, et al.
Publicado: (2018)

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
por: Orta, Manuel Luis, et al.
Publicado: (2014)

Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide Excision Repair
por: Mu, Hong, et al.
Publicado: (2018)

Histone H3 Lys79 methylation is required for efficient nucleotide excision repair in a silenced locus of Saccharomyces cerevisiae
por: Chaudhuri, Shubho, et al.
Publicado: (2009)

Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes
por: Yu, Yachuan, et al.
Publicado: (2013)

Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions
por: Reynolds, Pamela, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_32qpn0jcjlkk9qr9ruv5jqeck6