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Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression
The rapid transcriptional response to the transcription factor, glucocorticoid receptor (GR), including gene activation or repression, is mediated by the spatial association of genes with multiple GR binding sites (GBSs) over large genomic distances. However, only a minority of the GBSs have indepen...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262608/ https://www.ncbi.nlm.nih.gov/pubmed/35713523 http://dx.doi.org/10.1093/nar/gkac488 |