Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression

The rapid transcriptional response to the transcription factor, glucocorticoid receptor (GR), including gene activation or repression, is mediated by the spatial association of genes with multiple GR binding sites (GBSs) over large genomic distances. However, only a minority of the GBSs have indepen...

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Detalles Bibliográficos
Autores principales: Portuguez, Avital Sarusi, Grbesa, Ivana, Tal, Moran, Deitch, Rachel, Raz, Dana, Kliker, Limor, Weismann, Ran, Schwartz, Michal, Loza, Olga, Cohen, Leslie, Marchenkov-Flam, Libi, Sung, Myong-Hee, Kaplan, Tommy, Hakim, Ofir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262608/
https://www.ncbi.nlm.nih.gov/pubmed/35713523
http://dx.doi.org/10.1093/nar/gkac488

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