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A new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing
We report the discovery and functional characterization of a new bacterial tRNA species. The tRNA-Asp-AUC, from a fast-growing desert streptomycete, decodes GAU codons. In the absence of queuosine tRNA anticodon modification in streptomycetes, the new tRNA circumvents inefficient wobble base-pairing...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262613/ https://www.ncbi.nlm.nih.gov/pubmed/35699212 http://dx.doi.org/10.1093/nar/gkac502 |