A new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing

We report the discovery and functional characterization of a new bacterial tRNA species. The tRNA-Asp-AUC, from a fast-growing desert streptomycete, decodes GAU codons. In the absence of queuosine tRNA anticodon modification in streptomycetes, the new tRNA circumvents inefficient wobble base-pairing...

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Detalles Bibliográficos
Autores principales: Chen, Ximing, Li, Shuyan, Zhang, Binglin, Sun, Haili, Wang, Jinxiu, Zhang, Wei, Meng, Wenbo, Chen, Tuo, Dyson, Paul, Liu, Guangxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262613/
https://www.ncbi.nlm.nih.gov/pubmed/35699212
http://dx.doi.org/10.1093/nar/gkac502

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