Cargando…

MarcoPolo: a method to discover differentially expressed genes in single-cell RNA-seq data without depending on prior clustering

The standard analysis pipeline for single-cell RNA-seq data consists of sequential steps initiated by clustering the cells. An innate limitation of this pipeline is that an imperfect clustering result can irreversibly affect the succeeding steps. For example, there can be cell types not well disting...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Chanwoo, Lee, Hanbin, Jeong, Juhee, Jung, Keehoon, Han, Buhm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262626/
https://www.ncbi.nlm.nih.gov/pubmed/35420135
http://dx.doi.org/10.1093/nar/gkac216