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Inflammasome activation: from molecular mechanisms to autoinflammation

Inflammasomes are assembled by innate immune sensors that cells employ to detect a range of danger signals and respond with pro‐inflammatory signalling. Inflammasomes activate inflammatory caspases, which trigger a cascade of molecular events with the potential to compromise cellular integrity and r...

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Detalles Bibliográficos
Autores principales: Lara‐Reyna, Samuel, Caseley, Emily A, Topping, Joanne, Rodrigues, François, Jimenez Macias, Jorge, Lawler, Sean E, McDermott, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262628/
https://www.ncbi.nlm.nih.gov/pubmed/35832835
http://dx.doi.org/10.1002/cti2.1404