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Sorafenib Attenuates Fibrotic Hepatic Injury Through Mediating Lysine Crotonylation

BACKGROUND: Liver fibrosis is an independent contributor of chronic liver diseases, and regressing liver fibrosis is considered a potential therapeutic target for chronic liver diseases. We aimed to explore the effects and mechanism of sorafenib in liver fibrosis. METHODS: Male Sprague Dawley (SD) r...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Feng, Ji, Shaoxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262635/
https://www.ncbi.nlm.nih.gov/pubmed/35812135
http://dx.doi.org/10.2147/DDDT.S368306