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Fancd2os Reduces Testosterone Production by Inhibiting Steroidogenic Enzymes and Promoting Cellular Apoptosis in Murine Testicular Leydig Cells
BACKGROUND: It is well-established that serum testosterone in men decreases with age, yet the underlying mechanism of this change remains elusive. METHODS: The expression patterns of Fancd2 opposite-strand (Fancd2os) in BALB/c male mice and testicular tissue derived cell lines (GC-1, GC-2, TM3, and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262688/ https://www.ncbi.nlm.nih.gov/pubmed/35798552 http://dx.doi.org/10.3803/EnM.2022.1431 |