Cargando…

Vitamin D Receptor Upregulates Tight Junction Protein Claudin-5 against Colitis-Associated Tumorigenesis

Tight junctions are essential for barrier integrity, inflammation, and cancer. Vitamin D and the vitamin D receptor (VDR) play important roles in colorectal cancer (CRC). Using the human CRC database, we found colonic VDR expression was low and significantly correlated with a reduction of Claudin-5...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yongguo, Garrett, Shari, Carroll, Robert E., Xia, Yinglin, Sun, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262815/
https://www.ncbi.nlm.nih.gov/pubmed/35338345
http://dx.doi.org/10.1038/s41385-022-00502-1