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Vitamin D Receptor Upregulates Tight Junction Protein Claudin-5 against Colitis-Associated Tumorigenesis
Tight junctions are essential for barrier integrity, inflammation, and cancer. Vitamin D and the vitamin D receptor (VDR) play important roles in colorectal cancer (CRC). Using the human CRC database, we found colonic VDR expression was low and significantly correlated with a reduction of Claudin-5...
Autores principales: | Zhang, Yongguo, Garrett, Shari, Carroll, Robert E., Xia, Yinglin, Sun, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262815/ https://www.ncbi.nlm.nih.gov/pubmed/35338345 http://dx.doi.org/10.1038/s41385-022-00502-1 |
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