T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62

As a transcription factor that promotes cell growth, proliferation, and apoptosis, c-MYC (MYC) expression in the cell is tightly controlled. Disruption of oncogenic signaling pathways in human cancers can increase MYC protein stability, due to altered phosphorylation ratios at two highly conserved s...

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Detalles Bibliográficos
Autores principales: Daniel, Colin J., Pelz, Carl, Wang, Xiaoyan, Munks, Michael W., Ko, Aaron, Murugan, Dhaarini, Byers, Sarah A., Juarez, Eleonora, Taylor, Karyn L., Fan, Guang, Coussens, Lisa M., Link, Jason M., Sears, Rosalie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Tumor Microenvironment and Immunobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
https://www.ncbi.nlm.nih.gov/pubmed/35380701
http://dx.doi.org/10.1158/1541-7786.MCR-21-0560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
https://www.ncbi.nlm.nih.gov/pubmed/35380701
http://dx.doi.org/10.1158/1541-7786.MCR-21-0560

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