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High rates of plasmid cotransformation in E. coli overturn the clonality myth and reveal colony development

The concept of DNA transfer between bacteria was put forth by Griffith in 1928. During the dawn of molecular cloning of DNA in the 1980s, Hanahan described how the transformation of DNA plasmids into bacteria would allow for cloning of DNA fragments. Through this foundational work, it is widely taug...

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Detalles Bibliográficos
Autores principales: Tomoiaga, Delia, Bubnell, Jaclyn, Herndon, Liam, Feinstein, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262894/
https://www.ncbi.nlm.nih.gov/pubmed/35798773
http://dx.doi.org/10.1038/s41598-022-14598-9