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Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis

Sepsis is defined as a life-threatening organ dysfunction caused by an inappropriate host response to infection. The presence of oxidative stress and inflammatory mediators in sepsis leads to dysregulated gene expression, leading to a hyperinflammatory response. Environmental conditions play an impo...

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Detalles Bibliográficos
Autores principales: Córneo, Emily, Michels, Monique, Abatti, Mariane, Vieira, Andriele, Gonçalves, Renata Casagrande, Gabriel, Filipe Fernandes, Borges, Heloisa, Goulart, Amanda, da Silva Matos, Natan, Dominguini, Diogo, Varela, Roger, Valvassori, Samira S., Dal-Pizzol, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262921/
https://www.ncbi.nlm.nih.gov/pubmed/35798809
http://dx.doi.org/10.1038/s41598-022-14660-6