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Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis
Sepsis is defined as a life-threatening organ dysfunction caused by an inappropriate host response to infection. The presence of oxidative stress and inflammatory mediators in sepsis leads to dysregulated gene expression, leading to a hyperinflammatory response. Environmental conditions play an impo...
Autores principales: | Córneo, Emily, Michels, Monique, Abatti, Mariane, Vieira, Andriele, Gonçalves, Renata Casagrande, Gabriel, Filipe Fernandes, Borges, Heloisa, Goulart, Amanda, da Silva Matos, Natan, Dominguini, Diogo, Varela, Roger, Valvassori, Samira S., Dal-Pizzol, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262921/ https://www.ncbi.nlm.nih.gov/pubmed/35798809 http://dx.doi.org/10.1038/s41598-022-14660-6 |
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