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Characterization of regulatory transcriptional mechanisms in hepatocyte lipotoxicity

Non-alcoholic fatty liver disease is a continuum of disorders among which non-alcoholic steatohepatitis (NASH) is particularly associated with a negative prognosis. Hepatocyte lipotoxicity is one of the main pathogenic factors of liver fibrosis and NASH. However, the molecular mechanisms regulating...

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Detalles Bibliográficos
Autores principales: Pérez-Schindler, Joaquín, Vargas-Fernández, Elyzabeth, Karrer-Cardel, Bettina, Ritz, Danilo, Schmidt, Alexander, Handschin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262951/
https://www.ncbi.nlm.nih.gov/pubmed/35798791
http://dx.doi.org/10.1038/s41598-022-15731-4