Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation

The unfolded protein response (UPR) is an adaptive stress response pathway that is essential for cancer cell survival under endoplasmic reticulum stress such as during glucose starvation. In this study, we identified spautin-1, an autophagy inhibitor that suppresses ubiquitin-specific peptidase 10 (...

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Detalles Bibliográficos
Autores principales: Kunimasa, Kazuhiro, Ikeda-Ishikawa, Chika, Tani, Yuri, Tsukahara, Satomi, Sakurai, Junko, Okamoto, Yuka, Koido, Masaru, Dan, Shingo, Tomida, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262966/
https://www.ncbi.nlm.nih.gov/pubmed/35798783
http://dx.doi.org/10.1038/s41598-022-15673-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262966/
https://www.ncbi.nlm.nih.gov/pubmed/35798783
http://dx.doi.org/10.1038/s41598-022-15673-x

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