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Duplication of 8q24 in Chronic Lymphocytic Leukemia: Cytogenetic and Molecular Biologic Analysis of MYC Aberrations

Chronic lymphocytic leukemia (CLL) with cytogenetics findings, such as complex karyotype and deletions of TP53 or ATM, is associated with adverse clinical outcomes. Additional chromosomal abnormalities further stratify patients into groups with diverse prognoses. Gain of 8q24 is one of the abnormali...

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Detalles Bibliográficos
Autores principales: Ondroušková, Eva, Bohúnová, Michaela, Závacká, Kristýna, Čech, Patrik, Šmuhařová, Petra, Boudný, Miroslav, Oršulová, Martina, Panovská, Anna, Radová, Lenka, Doubek, Michael, Plevová, Karla, Jarošová, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263084/
https://www.ncbi.nlm.nih.gov/pubmed/35814434
http://dx.doi.org/10.3389/fonc.2022.859618