Population Pharmacokinetic Model of AST-001, L-Isomer of Serine, Combining Endogenous Production and Exogenous Administration in Healthy Subjects

AST-001 is an L-isomer of serine that has protective effects on neurological disorders. This study aimed to establish a population pharmacokinetic (PK) model of AST-001 in healthy Korean to further propose a fixed-dose regimen in pediatrics. The model was constructed using 648 plasma concentrations...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Soyoung, Hwang, Su-Kyeong, Nam, Hee-Sook, Cho, Jung-Sook, Chung, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263096/
https://www.ncbi.nlm.nih.gov/pubmed/35814222
http://dx.doi.org/10.3389/fphar.2022.891227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263096/
https://www.ncbi.nlm.nih.gov/pubmed/35814222
http://dx.doi.org/10.3389/fphar.2022.891227

Ejemplares similares