HOTAIR/miR-1277-5p/ZEB1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer

The hypoxic microenvironment contributes to the chemoresistance of many malignant tumors including colorectal cancer (CRC). Accumulating studies have indicated that long non-coding RNAs (lncRNAs) play important roles in chemotherapy resistance. In this study, we aimed to determine the effect of lncR...

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Detalles Bibliográficos
Autores principales: Weng, Xingyue, Liu, Hao, Ruan, Jian, Du, Miaoyan, Wang, Lingjie, Mao, Jiayan, Cai, Ying, Lu, Xuemei, Chen, Wei, Huang, Yaqing, Zhi, Xiao, Shan, Jianzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263107/
https://www.ncbi.nlm.nih.gov/pubmed/35798695
http://dx.doi.org/10.1038/s41420-022-01096-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263107/
https://www.ncbi.nlm.nih.gov/pubmed/35798695
http://dx.doi.org/10.1038/s41420-022-01096-0

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