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Bimodal regulation of axonal transport by the GDNF-RET signalling axis in healthy and diseased motor neurons
Deficits in axonal transport are one of the earliest pathological outcomes in several models of amyotrophic lateral sclerosis (ALS), including SOD1(G93A) mice. Evidence suggests that rescuing these deficits prevents disease progression, stops denervation, and extends survival. Kinase inhibitors have...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263112/ https://www.ncbi.nlm.nih.gov/pubmed/35798698 http://dx.doi.org/10.1038/s41419-022-05031-0 |